Uncategorized

Costs of Endocrine Disrupting Chemicals

The aim of this study was to quantify the disease burdens and related economic costs due to exposure to endocrine-disrupting chemicals (EDCs) during 2010 in both the USA and Europe in 2010.  The authors used existing models for assessing epidemiological and toxicological studies to reach consensus on probabilities of causation for 15 exposure-response relations between substances and disorders.

Overall, the disease costs for EDCs were much higher in the USA ($ 340 billion; 2.3% of GDP) than in Europe ($ 217 billion; 1.3% of GDP).  The difference was driven mainly by loss of IQ points due to polybraminated diphenyl ethers in the USA and organophospate pesticides in Europe.

Endocrine Disruptor Costs in USA and Europe in 2010

AgentUSAEuropeUS Costs (2010 US$)EU costs (US $)
PBDE and IQ point loss & intellectual disability11 million IQ points and 43,000 cases873,000 IQ points and 3290 cases266 billion12.6 billion
Organophosphate pesticides and IQ point loss/ intellectual disability1.8 million IQ points lost and 7500 cases13 million IQ points lost and 59,300 cases44.7 billion194.0 billion
Dichlorodiphenyltricholorethane and childhood obesity857 cases1555 cases29.6 million32.7 million
Dichlordiphenyltricholorethane and adult diabetes24,900 cases28,200 cases1.8 billion1.1 billion
Di-2-ethylhexylphthalate and adult obesity5,900 cases53,900 cases1.7 billion20.8 billion
Di-2-ethylhexylphthalate and adult diabetes1,300 cases20,500 cases91.4 million807.2 million
Bisphenol A and childhood obesity33,000 cases42,400 cases2.4 billion2.0 billion
PBDE and testicular cancer3,600 cases6,830 cases81.5 million1.1 billion
PBDE and cryptorchidism4,300 cases4,615 cases35.7 million172.6 million
Benzylphtalates & butylphthalates & male infertility240,100618,0002.5 billion6.3 billion
Phthalates and low testosterone resulting in increased early mortality10,700 attributable deaths24,800 attributable deaths8.8 billion10.6 billion
Multiple exposures and ADHD4,400 cases19,400-31,200 cases698.0 million2.3 billion
Multiple exposures and autism787 cases (boys) and 754 cases (girls)316 cases1.0 billion (boys) and 984 million (girls)265.1 million
Dichlorodiphenyltricholoroethane and fibroids37,000 cases56,700 cases259 million216.8 million
Di-2-ethylhexylphthalate and endometriosis86,000 cases145,000 cases47.0 billion1.7 billion
Cost per person (in 2010)$ 1,050 per person$ 292 per person

The studies conclusion was that the disease costs of EDCs were much higher in the USA than in Europe.

And if that isn’t bad enough, see below for the results of a 2011 study that most plastics end up releasing endocrine modifying chemicals:

 

The government is aware of the problem – to learn more see here & here. A list of the top culprits is here (they are even in cleaning products  – here is how to avoid this source).

Here are our responses to this information: we store all our food in steel & glass, we never heat food in plastic containers, we buy foods in glass bottles (and to avoid canned foods) as well as buying organic produce.

References

Exposure to endocrine-disrupting chemical in the USA: a population-based disease burden and cost analysis.  TM Attina et al.  Lancet Diabetes Endocrinology 2016:4(12):996-1003

 

Subhas Ganguli

Dr Subhas Ganguli is a Canadian gastroenterologist with an interest in the role of food in the prevention of disease. In November 2019 he passed the Board Exam of the American College of Lifestyle Medicine.

Leave a Reply

Your email address will not be published. Required fields are marked *